If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure will reduce the risk of strokes and heart attacks.

Is aliskiren safe?

Aliskiren is effective in reducing blood pressure (BP) and is well tolerated. The incidence of adverse events and the number of study discontinuations as a result of adverse events during aliskiren treatment were relatively low and generally not dissimilar from placebo.

What are the side effects of aliskiren?

Aliskiren may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• diarrhea.
• stomach pain.
• heartburn.
• cough.
• rash.
• dizziness.
• headache.
• back pain.

Is aliskiren safe in CKD?

Several clinical studies have demonstrated that aliskiren is effective on CKD (Table 1).

Does aliskiren cause joint pain?

joint pain or swelling, stuffy nose, or. sore throat.

What blood pressure meds contain aliskiren?

Aliskiren is found in the following medications:

• Amturnide (aliskiren hemifumarate, amlodipine besylate, and hydrochlorothiazide)
• Tekturna (aliskiren hemifumarate)
• Tekturna HCT (aliskiren hemifumarate and hydrochlorothiazide)
• Tekamlo (aliskiren hemifumarate and amlodipine besylate)

What is aliskiren 150 mg used for?

This medication is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Aliskiren works by relaxing blood vessels so blood can flow more easily. It belongs to a class of drugs known as direct renin inhibitors.

What is the medical term aliskiren?

What is aliskiren? Aliskiren is blood pressure medicine. It works by decreasing substances in the body that narrow blood vessels and raise blood pressure. Aliskiren is used to treat high blood pressure (hypertension).

Is aliskiren a diuretic?

Aliskiren works by relaxing blood vessels so blood can flow more easily. It belongs to a class of drugs known as direct renin inhibitors. Hydrochlorothiazide causes your body to get rid of extra salt and water by making more urine. It is called a “water pill” or diuretic.

Does aliskiren increase blood pressure?

We found that aliskiren, which lowered blood pressure (BP) effectively in patients with mild-to-moderate hypertension, was similar to HCTZ but inferior to CCBs in BP reduction, response rates and control rates.

Can chlorthalidone cause renal failure?

Chlorthalidone increased the risk of the following side effects when compared to hydrochlorothiazide: Low potassium levels (hypokalemia), nearly three times greater risk. Low sodium levels (hyponatremia), 31 percent greater risk. Acute kidney failure, 37 percent greater risk.

Is amlodipine safe in renal failure?

The drug was rated as of clinical benefit in 27 of the 35 patients (77.1%), and as slightly beneficial in another 5 patients (14.3%). Thus, amlodipine significantly decreased the blood pressure while causing little or no aggravation of renal dysfunction in hypertensive patients with renal impairment.

Does Valsartan cause kidney damage?

If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure.

What is a common side effect of nitroglycerin?

Headache, dizziness, lightheadedness, nausea, flushing, and burning/tingling under the tongue may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Headache is often a sign that this medication is working.

How does aliskiren reduce blood pressure?

Aliskiren, a novel direct renin inhibitor, lowers blood pressure by decreasing renin activity, and angiotensin I and II levels. At the approved dosage (150-300 mg once daily), it reduces systolic blood pressure by 12-16 mm Hg and diastolic blood pressure by 2-12 mm Hg.