Statins and the elderly recent evidence and current indications

  • Statin therapy produces significant reductions in major vascular events irrespective of age, but there is less direct evidence of benefit among patients older than 75 years who do not already have evidence of occlusive vascular disease. This limitation is now being addressed by further trials.

When Should statins be stopped in elderly?

Most societies, including the ACC and AHA, recommend shared decision making in this subgroup of patients. Now, a new study published this past week in the European Heart Journal suggests that discontinuing statins in patients older than 75 years of age may actually increase the risk of hospital admissions by 33%.

Should you take statins if you are over 70?

Adults age 75 and older may not need statins . Many older adults have high cholesterol. Their doctors usually prescribe statins to prevent heart disease. But for older people, there is no clear evidence that high cholesterol leads to heart disease or death.

Do statins reduce all cause mortality?

171819 In participants with diabetes, however, statins significantly reduced the incidence of atherosclerotic CVD, by 24%, and all cause mortality , by 16%, in participants aged 75-84 years.

When should you start statin primary prevention?

Primary ASCVD prevention requires assessing risk factors beginning in childhood. For those <19 years of age with familial hypercholesterolemia, a statin is indicated. For young adults (ages 20-39 years), priority should be given to estimating lifetime risk and promoting a healthy lifestyle.

Do statins age you faster?

Telomerase activity is associated with longer telomeres. Statins do have side effects, all medication does to some extent. And some of those side effects reported could also be deemed to be signs of premature aging. Memory loss and weakness or fatigue are both listed under ‘uncommon side effects’ on the NHS website.

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What should a 70 year old woman’s cholesterol be?

In general, healthy cholesterol levels for seniors are total cholesterol of below 200 mg/dl, including an LDL cholesterol level less than 100 mg/dl, and an HDL cholesterol level greater than 40 mg/dl for men or 50 mg/dl for women.

Why you should never take statins?

Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins .

Which is better Lipitor or Crestor?

Which Statin is Better : Lipitor or Crestor ? Lipitor and Crestor are both effective statins that lower levels of “bad” cholesterol and increase levels of “ good ” cholesterol. While Crestor is the more potent statin, both medications are effective and have slightly different side effects and drug interactions.

Do you have to stay on statins forever?

Statins are typically very successful at lowering cholesterol, but they only work as long as you ‘ re taking them. Therefore, most people who begin taking a statin medication will likely take it for the rest of their lives.

Do statins clear plaque from arteries?

Statins help lower low-density lipoprotein (LDL) cholesterol, also known as “bad” cholesterol, in the blood. They draw cholesterol out of plaque and stabilize plaque , Blaha says.

Do statins really reduce heart attacks?

Studies show that statins can lower the risk of heart attack and stroke. Statins provide the most benefit for people at high risk of heart attack and stroke.

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Should statins be used in primary prevention?

Statins may be overprescribed for the primary prevention of cardiovascular disease (CVD), according to a modeling analysis of benefits and harm. Statins are likely to provide net benefits at substantially higher 10-year CVD risk thresholds than the 7.5% to 10% thresholds noted by most guidelines, according to Milo A.

What are the new statin guidelines?

Moderate-intensity statin (atorvastatin, 10-20 mg; rosuvastatin, 5-10 mg; simvastatin, 20-40 mg; pravastatin, 40-80 mg; or lovastatin, 40 mg) is recommended for patients 75 or older who have ASCVD; diabetics whose 10-year ASCVD risk is below 7.5 percent; and anyone who cannot tolerate a high-dose statin .

What is primary prevention of CVD?

Primary prevention of CVD . • Refers to interventions that aim to. prevent or delay the onset of. cardiovascular disease in people who. have no clinical evidence of CVD .

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